PYGL CLIA Kit for Human(Homo sapiens) | EIAab.comPYGL CLIA Kit for Human(Homo sapiens)

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Index > Protein center > PYGL(Gene name) > Human

PYGL (Gene name),

Glycogen phosphorylase, liver form (Protein name ), PYGL_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

PYGL;

Protein name:

Glycogen phosphorylase, liver form;

Alternative:

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Homodimer. Dimers associate into a tetramer to form the enzymatically active phosphorylase A. Interacts with PPP1R3B.

Function:

Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

Subcellular Location:

N/A

Protein Attributes:

Sequence length:

847

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

550:

600:

650:

700:

750:

800:

847:

MVLKNIAASG | KFSSDRTIKE | YAQNIWNVEP | SDLKISLSNE | SNKVNGN

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

UniGene:

Hs.282417

KEGG:

hsa:5836

String:

P06737

STRING:

9606.ENSP00000216392

SMR:

P06737

MIM:

232700

Pfam:

PF00343

Uniprot:

P06737

FOR

ELISA Kit for Human Glycogen phosphorylase, liver form

Cat.:

E0849r

Price:

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Manual:

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Packing:

96T

Range:

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ELISA Kit for Human Glycogen phosphorylase, liver form

Cat.:

E0849h

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Manual:

Looking for manual.

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Packing:

96T

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ELISA Kit for Human Glycogen phosphorylase, liver form

Cat.:

E0849m

Price:

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MSDS:

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Packing:

96T

ELISA Kit for Human Glycogen phosphorylase, liver form

Cat.:

E0849b

Price:

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MSDS:

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Packing:

96T

CLIA Kit for Human Glycogen phosphorylase, liver form

Cat.:

U0849h

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Human Glycogen phosphorylase, liver form

Cat.:

U0849m

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Human Glycogen phosphorylase, liver form

Cat.:

U0849r

Price:

Please sign in first.

Manual:

Looking for manual.

MSDS:

Please sign in first.

Packing:

96T

Range:

Please sign in first.

CLIA Kit for Human Glycogen phosphorylase, liver form

Cat.:

U0849b

Price:

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MSDS:

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Packing:

96T

Polyclonal Antibody for Human Glycogen phosphorylase, liver form

Cat.:

P0849Rb-m

Price:

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human Glycogen phosphorylase, liver form

Cat.:

P0849Rb-r

Price:

Please sign in first.

Packing:

40ug/0.2ml

Polyclonal Antibody for Human Glycogen phosphorylase, liver form

Cat.:

P0849Rb-h

Price:

Please sign in first.

Packing:

40ug/0.2ml

Monoclonal Antibody for Human Glycogen phosphorylase, liver form

Protein for Human Glycogen phosphorylase, liver form

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Sequence analysis of the cDNA encoding human liver glycogen phosphorylase reveals tissue-specific codon usage."
Newgard C.B. , Nakano K. , Hwang P.K. , Fletterick R.J.
Proc. Natl. Acad. Sci. U.S.A.83:8132-8136(1986) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);VARIANT PRO-425
tissue: Liver.
2.

Carty M.D. , Clancy Y.C. , Soeller W.C.
Submitted (1998-05) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
tissue: Liver.
3.

"Identification of a mutation in liver glycogen phosphorylase in glycogen storage disease type VI."
Chang S. , Rosenberg M.J. , Morton H. , Francomano C.A. , Biesecker L.G.
Hum. Mol. Genet.7:865-870(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
4.

"Mutations in the liver glycogen phosphorylase gene 'PYGL' underlying glycogenosis type VI."
Burwinkel B. , Bakker H.D. , Herschkovitz E. , Moses S.W. , Shin Y.S. , Kilimann M.W.
Am. J. Hum. Genet.62:785-791(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);VARIANTS GSD6 SER-339 AND LYS-377;VARIANT ILE-222
tissue: Blood.
5.

"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2);VARIANT SER-845
6.

"The DNA sequence and analysis of human chromosome 14."
Heilig R. , Eckenberg R. , Petit J.-L. , Fonknechten N. , Da Silva C. , Cattolico L. , Levy M. , Barbe V. , De Berardinis V. , Ureta-Vidal A. , Pelletier E. , Vico V. , Anthouard V. , Rowen L. , Madan A. , Qin S. , Sun H. , Du H. , more...
Nature421:601-607(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
7.

Mural R.J. , Istrail S. , Sutton G.G. , Florea L. , Halpern A.L. , Mobarry C.M. , Lippert R. , Walenz B. , Shatkay H. , Dew I. , Miller J.R. , Flanigan M.J. , Edwards N.J. , Bolanos R. , Fasulo D. , Halldorsson B.V. , Hannenhalli S. , Turner R. , more...
Submitted (2005-09) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
8.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
tissue: Placenta.
tissue: Skin.
tissue: Uterus.
9.

"McArdle's & Hers' diseases: glycogen phosphorylase transcriptional expression in human tissues."
Gorin F.A. , Mullinax R.L. , Ignacio P.C. , Neve R.L. , Kurnit D.M.
J. Neurogenet.4:293-308(1987) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 482-847 (ISOFORM 1)
tissue: Fetal brain.
10.

"Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."
Gauci S. , Helbig A.O. , Slijper M. , Krijgsveld J. , Heck A.J. , Mohammed S.
Anal. Chem.81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT ALA-2;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS];CLEAVAGE OF INITIATOR METHIONINE [LARGE SCALE ANALYSIS]
11.

"Initial characterization of the human central proteome."
Burkard T.R. , Planyavsky M. , Kaupe I. , Breitwieser F.P. , Buerckstuemmer T. , Bennett K.L. , Superti-Furga G. , Colinge J.
BMC Syst. Biol.5:17-17(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
12.

"N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB."
Van Damme P. , Lasa M. , Polevoda B. , Gazquez C. , Elosegui-Artola A. , Kim D.S. , De Juan-Pardo E. , Demeyer K. , Hole K. , Larrea E. , Timmerman E. , Prieto J. , Arnesen T. , Sherman F. , Gevaert K. , Aldabe R.
Proc. Natl. Acad. Sci. U.S.A.109:12449-12454(2012) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
13.

"Human liver glycogen phosphorylase inhibitors bind at a new allosteric site."
Rath V.L. , Ammirati M. , Danley D.E. , Ekstrom J.L. , Gibbs E.M. , Hynes T.R. , Mathiowetz A.M. , McPherson R.K. , Olson T.V. , Treadway J.L. , Hoover D.J.
Chem. Biol.7:677-682(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.2 ANGSTROMS)
14.

"Activation of human liver glycogen phosphorylase by alteration of the secondary structure and packing of the catalytic core."
Rath V.L. , Ammirati M. , LeMotte P.K. , Fennell K.F. , Mansour M.N. , Danley D.E. , Hynes T.R. , Schulte G.K. , Wasilko D.J. , Pandit J.
Mol. Cell6:139-148(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.4 ANGSTROMS);PHOSPHORYLATION AT SER-15
15.

"Structure-activity analysis of the purine binding site of human liver glycogen phosphorylase."
Ekstrom J.L. , Pauly T.A. , Carty M.D. , Soeller W.C. , Culp J. , Danley D.E. , Hoover D.J. , Treadway J.L. , Gibbs E.M. , Fletterick R.J. , Day Y.S. , Myszka D.G. , Rath V.L.
Chem. Biol.9:915-924(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.25 ANGSTROMS)

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